Hydroxide → 2-(difluoromethyl)-1-{[2-methyl-3-(trifluoromethyl)phenyl]methyl}-6-(4-morpholinyl)-1H-benzimidazole-4-carboxylic acid
Reaction equation
[CH2:37]1[O:38][CH2:39][CH2:40][CH2:41]1.[F:1][CH:2]([c:3]1[n:4][c:5]2[c:6]([n:7]1[CH2:8][c:9]1[c:10]([CH3:19])[c:11]([C:15]([F:16])([F:17])[F:18])[cH:12][cH:13][cH:14]1)[cH:20][c:21]([N:28]1[CH2:29][CH2:30][O:31][CH2:32][CH2:33]1)[cH:22][c:23]2[C:24](=[O:25])[O:26][CH3:27])[F:34].[Li+:36].[OH-:35]>>[F:1][CH:2]([c:3]1[n:4][c:5]2[c:6]([n:7]1[CH2:8][c:9]1[c:10]([CH3:19])[c:11]([C:15]([F:16])([F:17])[F:18])[cH:12][cH:13][cH:14]1)[cH:20][c:21]([N:28]1[CH2:29][CH2:30][O:31][CH2:32][CH2:33]1)[cH:22][c:23]2[C:24](=[O:25])[OH:26])[F:34]Participants
5
Reactant 4
Product 1
Sources & evidence
- ORD record
- ord-bcb6955b18f0463ebc0f0cfa657d83ac
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
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