Dimethylformamide → 2-(4-Benzyl-4-hydroxy-piperidin-1-yl)-N-[4-(tert-butyl-dimethyl-silanyloxy)-phenyl)-acetamide
Reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[Si:5]([O:6][c:7]1[cH:8][cH:9][c:10]([NH:13][C:14]([CH2:15][Cl:16])=[O:17])[cH:11][cH:12]1)([CH3:18])[CH3:19].[CH2:27]([c:28]1[cH:29][cH:30][cH:31][cH:32][cH:33]1)[C:34]1([OH:40])[CH2:35][CH2:36][NH:37][CH2:38][CH2:39]1.[CH3:20][CH2:21][N:22]([CH2:23][CH3:24])[CH2:25][CH3:26].[CH3:41][N:42]([CH3:43])[CH:44]=[O:45]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[Si:5]([O:6][c:7]1[cH:8][cH:9][c:10]([NH:13][C:14]([CH2:15][N:37]2[CH2:36][CH2:35][C:34]([CH2:27][c:28]3[cH:29][cH:30][cH:31][cH:32][cH:33]3)([OH:40])[CH2:39][CH2:38]2)=[O:17])[cH:11][cH:12]1)([CH3:18])[CH3:19]Participants
5
Sources & evidence
- ORD record
- ord-f15324cda47b4c39b4f56137a4f215ae
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
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