Hydrochloric Acid → 4-(2-fluoro-4-(methylthio)phenylamino)-N-(2-hydroxyethoxy)-1-methyl-6-oxo-1,6-dihydropyridazine-3-carboxamide

HRID 1558193Notes

Reaction equation

HRID 1558193 reaction equation
[CH3:29][CH2:30][O:31][C:32]([CH3:33])=[O:34].[ClH:28].[F:1][c:2]1[c:3]([NH:10][c:11]2[c:12]([C:19](=[O:20])[NH:21][O:22][CH2:23][CH2:24][O:25][CH:26]=[CH2:27])[n:13][n:14]([CH3:18])[c:15](=[O:17])[cH:16]2)[cH:4][cH:5][c:6]([S:8][CH3:9])[cH:7]1>>[F:1][c:2]1[c:3]([NH:10][c:11]2[c:12]([C:19](=[O:20])[NH:21][O:22][CH2:23][CH2:24][OH:25])[n:13][n:14]([CH3:18])[c:15](=[O:17])[cH:16]2)[cH:4][cH:5][c:6]([S:8][CH3:9])[cH:7]1

Participants

4

Reactant 3

HCID 313Hydrochloric AcidHCID 8857Ethyl AcetateHCID 866016154-(2-fluoro-4-(methylthio)phenylamino)-1-methyl-6-oxo-N-(2-(vinyloxy)ethoxy)-1,6-dihydropyridazine-3-carboxamide

Product 1

HCID 166671574-(2-fluoro-4-(methylthio)phenylamino)-N-(2-hydroxyethoxy)-1-methyl-6-oxo-1,6-dihydropyridazine-3-carboxamide

Sources & evidence

ORD record
ord-61be047655e14efdac912afebd0a208a
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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