Dichloromethane → HCID 68563994, compound

HRID 1558576Notes

Reaction equation

HRID 1558576 reaction equation
[CH2:50]([CH2:51][CH2:52][CH3:53])[S:54](=[O:55])(=[O:56])[Cl:57].[CH3:8][S:9](=[O:10])(=[O:11])[c:12]1[cH:13][c:14]2[c:18]([cH:19][cH:20]1)[N:17]([c:21]1[cH:22][c:23]([O:27][CH:28]3[CH2:29][CH2:30][N:31]([C:34]([O:35][C:36]([CH3:37])([CH3:38])[CH3:39])=[O:40])[CH2:32][CH2:33]3)[n:24][cH:25][n:26]1)[CH2:16][CH2:15]2.[CH:41]([N:42]([CH:43]([CH3:44])[CH3:45])[CH2:46][CH3:47])([CH3:48])[CH3:49].[Cl:58][CH2:59][Cl:60].[OH:1][C:2]([C:3]([F:4])([F:5])[F:6])=[O:7]>>[CH3:8][S:9](=[O:10])(=[O:11])[c:12]1[cH:13][c:14]2[c:18]([cH:19][cH:20]1)[N:17]([c:21]1[cH:22][c:23]([O:27][CH:28]3[CH2:29][CH2:30][N:31]([S:54]([CH2:50][CH2:51][CH2:52][CH3:53])(=[O:55])=[O:56])[CH2:32][CH2:33]3)[n:24][cH:25][n:26]1)[CH2:16][CH2:15]2

Participants

6

Reactant 5

HCID 6344DichloromethaneHCID 6422Trifluoroacetic acidHCID 754301-Butanesulfonyl chlorideHCID 81531DiisopropylethylamineHCID 25242414Tert-butyl 4-((6-(5-(methylsulfonyl)indolin-1-yl)pyrimidin-4-yl)oxy)piperidine-1-carboxylate

Product 1

HCID 68563994HCID 68563994, compound

Sources & evidence

ORD record
ord-cb4bf0df965a41c28f027dc815f9b26b
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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