Trifluoroacetic acid → 3-{2-[4-(4-Chloro-3-methoxy-phenyl)-piperazin-1-yl]-2-oxo-ethyl}-6-(2-hydroxy-ethoxy)-3H-benzooxazol-2-one
Reaction equation
[CH2:46]1[O:47][CH2:48][CH2:49][CH2:50]1.[Cl:1][c:2]1[c:3]([O:37][CH3:38])[cH:4][c:5]([N:8]2[CH2:9][CH2:10][N:11]([C:14]([CH2:15][n:16]3[c:17](=[O:35])[o:18][c:19]4[c:20]3[cH:21][cH:22][c:23]([O:25][CH2:26][CH2:27][O:28][CH:29]3[CH2:30][CH2:31][CH2:32][CH2:33][O:34]3)[cH:24]4)=[O:36])[CH2:12][CH2:13]2)[cH:6][cH:7]1.[F:39][C:40]([F:41])([F:42])[C:43]([OH:44])=[O:45]>>[Cl:1][c:2]1[c:3]([O:37][CH3:38])[cH:4][c:5]([N:8]2[CH2:9][CH2:10][N:11]([C:14]([CH2:15][n:16]3[c:17](=[O:35])[o:18][c:19]4[c:20]3[cH:21][cH:22][c:23]([O:25][CH2:26][CH2:27][OH:28])[cH:24]4)=[O:36])[CH2:12][CH2:13]2)[cH:6][cH:7]1Participants
4
Reactant 3
Product 1
Sources & evidence
- ORD record
- ord-5f272f26f11d43c2bac36183d3ce490b
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
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