Sodium ion → 8-(2,6-Dimethylbenzylamino)-2-hydroxymethyl-3-methylimidazo[1,2-a]pyridine

HRID 1558714Notes

Reaction equation

HRID 1558714 reaction equation
[Al+3:27].[CH3:1][c:2]1[c:3]([CH2:4][NH:5][c:6]2[c:7]3[n:8]([cH:9][cH:10][cH:11]2)[c:12]([CH3:20])[c:13]([C:15](=[O:16])[O:17][CH2:18][CH3:19])[n:14]3)[c:21]([CH3:25])[cH:22][cH:23][cH:24]1.[H-:26].[H-:29].[H-:30].[H-:31].[Li+:28].[Na+:34].[O:35]1[CH2:36][CH2:37][CH2:38][CH2:39]1.[OH-:33].[OH2:32]>>[CH3:1][c:2]1[c:3]([CH2:4][NH:5][c:6]2[c:7]3[n:8]([cH:9][cH:10][cH:11]2)[c:12]([CH3:20])[c:13]([CH2:15][OH:16])[n:14]3)[c:21]([CH3:25])[cH:22][cH:23][cH:24]1

Participants

9

Reactant 8

HCID 923Sodium ionHCID 961HydroxideHCID 962WaterHCID 8028TetrahydrofuranHCID 28486Lithium ionHCID 104727Aluminum CationHCID 166653Hydride4×HCID 22672581Ethyl 8-(2,6-dimethylbenzylamino)-3-methylimidazo[1,2-a]pyridine-2-carboxylate

Product 1

HCID 98826348-(2,6-Dimethylbenzylamino)-2-hydroxymethyl-3-methylimidazo[1,2-a]pyridine

Sources & evidence

ORD record
ord-61c57126d4a14860895700577f798f0a
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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