Chloride → tert-Butyl 2-(5-amino-4-(trans-4-hydroxycyclohexylamino)pyrimidin-2-ylamino)-4-fluorophenylcarbamate
Reaction equation
[C:34](=[O:35])([OH:36])[O-:37].[CH2:41]1[O:42][CH2:43][CH2:44][CH2:45]1.[Cl-:40].[F:1][c:2]1[cH:3][c:4]([NH:16][c:17]2[n:18][cH:19][c:20]([N+:31]([O-:32])=[O:33])[c:21]([NH:23][CH:24]3[CH2:25][CH2:26][CH:27]([OH:30])[CH2:28][CH2:29]3)[n:22]2)[c:5]([NH:8][C:9]([O:10][C:11]([CH3:12])([CH3:13])[CH3:14])=[O:15])[cH:6][cH:7]1.[Na+:38].[Na+:39]>>[F:1][c:2]1[cH:3][c:4]([NH:16][c:17]2[n:18][cH:19][c:20]([NH2:31])[c:21]([NH:23][CH:24]3[CH2:25][CH2:26][CH:27]([OH:30])[CH2:28][CH2:29]3)[n:22]2)[c:5]([NH:8][C:9]([O:10][C:11]([CH3:12])([CH3:13])[CH3:14])=[O:15])[cH:6][cH:7]1Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-94b653ffdb0849d18f34ffb619a6d088
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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