Tetrahydrofuran → 3-(3-Bromo-2-(4-fluorophenyl)furo[2,3-b]pyridin-5-yl)-4-chlorobenzoic acid
Reaction equation
[CH2:35]1[O:36][CH2:37][CH2:38][CH2:39]1.[CH3:40][CH2:41][O:42][C:43]([CH3:44])=[O:45].[Cl:9][c:10]1[c:11](-[c:19]2[cH:20][c:21]3[c:22]([n:23][cH:24]2)[o:25][c:26](-[c:28]2[cH:29][cH:30][c:31]([F:34])[cH:32][cH:33]2)[cH:27]3)[cH:12][c:13]([C:14](=[O:15])[OH:16])[cH:17][cH:18]1.[O:1]=[C:2]1[N:3]([Br:8])[C:4](=[O:5])[CH2:6][CH2:7]1>>[Br:8][c:27]1[c:21]2[cH:20][c:19](-[c:11]3[c:10]([Cl:9])[cH:18][cH:17][c:13]([C:14](=[O:15])[OH:16])[cH:12]3)[cH:24][n:23][c:22]2[o:25][c:26]1-[c:28]1[cH:29][cH:30][c:31]([F:34])[cH:32][cH:33]1Participants
5
Sources & evidence
- ORD record
- ord-6865d1e99dad447495bccd0374115da9
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
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