Hydrochloric Acid → N-biphenyl-4-yl-3-oxo-3-[4-(2-trifluoromethyl-benzyl)-piperazin-1-yl]-propionamide
Reaction equation
[Br:32][CH2:33][c:34]1[c:35]([C:40]([F:41])([F:42])[F:43])[cH:36][cH:37][cH:38][cH:39]1.[ClH:1].[K+:26].[K+:27].[O-:28][C:29]([O-:30])=[O:31].[O:44]=[CH:45][N:46]([CH3:47])[CH3:48].[OH2:49].[c:2]1(-[c:20]2[cH:21][cH:22][cH:23][cH:24][cH:25]2)[cH:3][cH:4][c:5]([NH:8][C:9]([CH2:10][C:11]([N:12]2[CH2:13][CH2:14][NH:15][CH2:16][CH2:17]2)=[O:18])=[O:19])[cH:6][cH:7]1>>[c:2]1(-[c:20]2[cH:21][cH:22][cH:23][cH:24][cH:25]2)[cH:3][cH:4][c:5]([NH:8][C:9]([CH2:10][C:11]([N:12]2[CH2:13][CH2:14][N:15]([CH2:33][c:34]3[c:35]([C:40]([F:41])([F:42])[F:43])[cH:36][cH:37][cH:38][cH:39]3)[CH2:16][CH2:17]2)=[O:18])=[O:19])[cH:6][cH:7]1Participants
8
Reactant 7
Product 1
Sources & evidence
- ORD record
- ord-54e6b391eb44451995f14967bca98824
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
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