Hydrochloric Acid → 4-Cyclopropyl-2-fluoroaniline

HRID 1560365Notes

Reaction equation

HRID 1560365 reaction equation
[Cl:48][C:49]([Cl:50])([O:51][C:52](=[O:53])[O:54][C:55]([Cl:56])([Cl:57])[Cl:58])[Cl:59].[Cl:61][CH2:62][Cl:63].[ClH:60].[NH2:1][CH:2]([c:3]1[cH:4][cH:5][c:6]([O:7][CH2:8][CH2:20][O:21][Si:22]([CH3:23])([CH3:24])[CH3:25])[cH:26][cH:27]1)[C:28]([NH:29][CH:30]([CH:31]([c:32]1[cH:33][cH:34][cH:35][cH:36][cH:37]1)[CH3:38])[C:39]([NH:9][c:10]1[c:11]([F:19])[cH:12][c:13]([CH:16]2[CH2:17][CH2:18]2)[cH:14][cH:15]1)=[O:40])=[O:41].[cH:42]1[cH:43][cH:44][n:45][cH:46][cH:47]1>>[NH2:9][c:10]1[c:11]([F:19])[cH:12][c:13]([CH:16]2[CH2:17][CH2:18]2)[cH:14][cH:15]1

Participants

6

Reactant 5

HCID 313Hydrochloric AcidHCID 1049PyridineHCID 6344DichloromethaneHCID 94429TriphosgeneHCID 68619166HCID 68619166, compound

Product 1

HCID 201000714-Cyclopropyl-2-fluoroaniline

Sources & evidence

ORD record
ord-0218f7d920784e7e8d13280702385549
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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