Tetrahydrofuran → 4-Hydroxy-6-[4-(2-hydroxyethoxy)phenyl]-3-phenethylsulfanyl-pyran-2-one

HRID 1560789Notes

Reaction equation

[BH4-:29].[Li+:30].[O:31]1[CH2:32][CH2:33][CH2:34][CH2:35]1.[OH:1][c:2]1[c:3]([S:20][CH2:21][CH2:22][c:23]2[cH:24][cH:25][cH:26][cH:27][cH:28]2)[c:4](=[O:19])[o:5][c:6](-[c:8]2[cH:9][cH:10][c:11]([O:12][CH2:13][C:14](=[O:15])[OH:16])[cH:17][cH:18]2)[cH:7]1>>[OH:1][c:2]1[c:3]([S:20][CH2:21][CH2:22][c:23]2[cH:24][cH:25][cH:26][cH:27][cH:28]2)[c:4](=[O:19])[o:5][c:6](-[c:8]2[cH:9][cH:10][c:11]([O:12][CH2:13][CH2:14][OH:15])[cH:17][cH:18]2)[cH:7]1

Participants

Reactant 4

HCID 8028Tetrahydrofuran

HCID 28123Borohydride

HCID 28486Lithium ion

HCID 546811772-(4-{4-hydroxy-2-oxo-3-[(2-phenylethyl)sulfanyl]-2H-pyran-6-yl}phenoxy)acetic acid

Product 1

HCID 547140774-Hydroxy-6-[4-(2-hydroxyethoxy)phenyl]-3-phenethylsulfanyl-pyran-2-one

Sources & evidence

ORD record: ord-1faa6acb0b9343b2a870776ab487fae6
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (1/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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