Dimethylformamide → N-(Cyclopropylmethyl)-2-((3,5-dichloropyridin-4-yl)amino)-1,7,7-trimethyl-7,8-dihydro-1H-benzofuro[4,5-d]imidazole-5-carboxamide

HRID 1561205Notes

Reaction equation

HRID 1561205 reaction equation
[B-:33]([F:34])([F:35])([F:36])[F:37].[CH2:60]1[O:61][CH2:62][CH2:63][CH2:64]1.[CH:28]1([CH2:31][NH2:32])[CH2:29][CH2:30]1.[Cl:1][c:2]1[cH:3][n:4][cH:5][c:6]([Cl:27])[c:7]1[NH:8][c:9]1[n:10][c:11]2[c:12]([n:13]1[CH3:14])[c:15]1[c:19]([c:20]([C:22](=[O:23])[OH:24])[cH:21]2)[O:18][C:17]([CH3:25])([CH3:26])[CH2:16]1.[O:55]=[CH:56][N:57]([CH3:58])[CH3:59].[n:38]1([O:39][C:40]([N:41]([CH3:42])[CH3:43])=[N+:44]([CH3:45])[CH3:46])[c:47]2[cH:48][cH:49][cH:50][cH:51][c:52]2[n:53][n:54]1>>[Cl:1][c:2]1[cH:3][n:4][cH:5][c:6]([Cl:27])[c:7]1[NH:8][c:9]1[n:10][c:11]2[c:12]([n:13]1[CH3:14])[c:15]1[c:19]([c:20]([C:22](=[O:24])[NH:32][CH2:31][CH:28]3[CH2:29][CH2:30]3)[cH:21]2)[O:18][C:17]([CH3:25])([CH3:26])[CH2:16]1

Participants

7

Reactant 6

HCID 6228DimethylformamideHCID 8028TetrahydrofuranHCID 26255TetrafluoroborateHCID 75646CyclopropanemethanamineHCID 130500O-benzotriazol-1-yl-tetramethyluroniumHCID 67502982HCID 67502982, compound

Product 1

HCID 56968487N-(Cyclopropylmethyl)-2-((3,5-dichloropyridin-4-yl)amino)-1,7,7-trimethyl-7,8-dihydro-1H-benzofuro[4,5-d]imidazole-5-carboxamide

Sources & evidence

ORD record
ord-0a6ef72993b944ae89ae0127ff524cac
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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