HRID1561616

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID923

Sodium ion

Na+

HCID6228

Dimethylformamide

C3H7NO

HCID81184

1,8-Diazabicyclo[5.4.0]undec-7-ene

C9H16N2

HCID166653

Hydride

H-

反应SMILES：CCOC(=O)c1cn(-c2ccc(F)cc2F)c2nc(Cl)c(F)cc2c1=O

HCID1268243

Ethyl 7-chloro-1-(2,4-difluorophenyl)-6-fluoro-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylate

C17H10ClF3N2O3

HCID4416939

1-Boc-3-hydroxypyrrolidine

C9H17NO3

PRODUCTS

产物

反应SMILES：CCOC(=O)c1cn(-c2ccc(F)cc2F)c2nc(OC3CCN(C(=O)OC(C)(C)C)C3)c(F)cc2c1=O

HCID15021553

未命名化合物

来源与证据

来源类型: Open Reaction Database
ORD记录: ord-9de823153cd74d50b47dbcf7221a2fcb
来源数据集: Training data from https://doi.org/10.1039/C8SC04228D (1/10)
DOI: 10.1039/C8SC04228D
来源说明: Training data from https://doi.org/10.1039/C8SC04228D (1/10)

反应SMILES

[C:27]([CH3:28])([CH3:29])([CH3:30])[O:31][C:32](=[O:33])[N:34]1[CH2:35][CH:36]([OH:39])[CH2:37][CH2:38]1.[CH2:40]1[CH2:41][CH2:42][C:43]2=[N:48][CH2:47][CH2:46][CH2:45][N:44]2[CH2:49][CH2:50]1.[F:1][c:2]1[c:3](-[n:9]2[cH:10][c:11]([C:22](=[O:23])[O:24][CH2:25][CH3:26])[c:12](=[O:21])[c:13]3[cH:14][c:15]([F:20])[c:16]([Cl:19])[n:17][c:18]23)[cH:4][cH:5][c:6]([F:8])[cH:7]1.[H-:51].[Na+:52].[O:53]=[CH:54][N:55]([CH3:56])[CH3:57]>>[F:1][c:2]1[c:3](-[n:9]2[cH:10][c:11]([C:22](=[O:23])[O:24][CH2:25][CH3:26])[c:12](=[O:21])[c:13]3[cH:14][c:15]([F:20])[c:16]([O:39][CH:36]4[CH2:35][N:34]([C:32]([O:31][C:27]([CH3:28])([CH3:29])[CH3:30])=[O:33])[CH2:38][CH2:37]4)[n:17][c:18]23)[cH:4][cH:5][c:6]([F:8])[cH:7]1