Pyridine → 2-[4-Fluoro-2-(1-tert-butoxycarbonylpiperidin-4-yloxy)benzoylamino]-N-(5-chloropyridin-2-yl)benzamide
Reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][CH:11]([O:14][c:15]2[c:16]([C:17](=[O:18])[OH:19])[cH:20][cH:21][c:22]([F:24])[cH:23]2)[CH2:12][CH2:13]1.[CH2:54]([Cl:55])[Cl:56].[Cl:31][C:32]([C:33]([Cl:34])=[O:35])=[O:36].[Cl:37][c:38]1[cH:39][cH:40][c:41]([NH:44][C:45]([c:46]2[c:47]([NH2:52])[cH:48][cH:49][cH:50][cH:51]2)=[O:53])[n:42][cH:43]1.[O:57]=[CH:58][N:59]([CH3:60])[CH3:61].[cH:25]1[cH:26][cH:27][n:28][cH:29][cH:30]1>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][CH:11]([O:14][c:15]2[c:16]([C:17](=[O:19])[NH:52][c:47]3[c:46]([C:45]([NH:44][c:41]4[cH:40][cH:39][c:38]([Cl:37])[cH:43][n:42]4)=[O:53])[cH:51][cH:50][cH:49][cH:48]3)[cH:20][cH:21][c:22]([F:24])[cH:23]2)[CH2:12][CH2:13]1Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-3df89d2c119c43f187eb71abd3fb7d21
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
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