Dimethylformamide → {4-[(6-Amino-1,3-dimethyl-2,4-dioxo-1,2,3,4-tetrahydro-pyrimidin-5-ylcarbamoyl)-methyl]-phenyl}-carbamic acid tert-butyl ester

HRID 1562436Notes

Reaction equation

HRID 1562436 reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[NH:8][c:9]1[cH:10][cH:11][c:12]([CH2:15][C:16](=[O:17])[OH:18])[cH:13][cH:14]1.[CH3:31][N:32]([CH3:33])[CH:34]=[O:35].[CH3:36][N:37]([CH3:38])[c:39]1[cH:40][cH:41][n:42][cH:43][cH:44]1.[NH2:19][c:20]1[c:21](=[O:30])[n:22]([CH3:29])[c:23](=[O:28])[n:24]([CH3:27])[c:25]1[NH2:26]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[NH:8][c:9]1[cH:10][cH:11][c:12]([CH2:15][C:16](=[O:18])[NH:19][c:20]2[c:21](=[O:30])[n:22]([CH3:29])[c:23](=[O:28])[n:24]([CH3:27])[c:25]2[NH2:26])[cH:13][cH:14]1

Participants

5

Reactant 4

HCID 6228DimethylformamideHCID 142844-(Dimethylamino)pyridineHCID 795015,6-Diamino-1,3-dimethyluracilHCID 28249932-(4-((Tert-butoxycarbonyl)amino)phenyl)acetic acid

Product 1

HCID 58762837{4-[(6-Amino-1,3-dimethyl-2,4-dioxo-1,2,3,4-tetrahydro-pyrimidin-5-ylcarbamoyl)-methyl]-phenyl}-carbamic acid tert-butyl ester

Sources & evidence

ORD record
ord-0333208f2b3f46d7872bdb258c73b962
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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