Tetrahydrofuran → {5-[(2-Chloro-3,5-dimethoxy-phenylamino)-methyl]-2-methylsulfanyl-pyrimidin-4-yl}-ethyl-amine
Reaction equation
[Al+3:26].[CH2:31]1[O:32][CH2:33][CH2:34][CH2:35]1.[Cl:1][c:2]1[c:3]([N:12]=[CH:13][c:14]2[c:15]([NH:22][CH2:23][CH3:24])[n:16][c:17]([S:20][CH3:21])[n:18][cH:19]2)[cH:4][c:5]([O:10][CH3:11])[cH:6][c:7]1[O:8][CH3:9].[H-:25].[H-:28].[H-:29].[H-:30].[Li+:27]>>[Cl:1][c:2]1[c:3]([NH:12][CH2:13][c:14]2[c:15]([NH:22][CH2:23][CH3:24])[n:16][c:17]([S:20][CH3:21])[n:18][cH:19]2)[cH:4][c:5]([O:10][CH3:11])[cH:6][c:7]1[O:8][CH3:9]Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-c6746d0c356f4b4aa04e784b5aaf49ad
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
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