Bicarbonate Ion → 3-Cyclopropylpyridin-2-amine

HRID 1562872Notes

Reaction equation

HRID 1562872 reaction equation
[C:33](=[O:34])([O-:35])[OH:36].[C:51]([OH:52])([CH3:53])([CH3:54])[CH3:55].[CH2:45]1[O:46][CH2:47][CH2:48][O:49][CH2:50]1.[CH3:38][OH:39].[CH3:40][N:41]([CH3:42])[CH:43]=[O:44].[CH3:56][CH2:57][N:58]([CH2:59][CH3:60])[CH2:61][CH3:62].[CH:1]1([c:4]2[c:5]([C:10]([O:11][CH3:12])=[O:13])[n:6][cH:7][cH:8][cH:9]2)[CH2:2][CH2:3]1.[Na+:15].[Na+:37].[OH-:14].[c:16]1([P:17]([c:20]2[cH:21][cH:22][cH:23][cH:24][cH:25]2)(=[O:26])[N:30]=[N+:18]=[N-:19])[cH:27][cH:28][cH:29][cH:31][cH:32]1>>[CH:1]1([c:4]2[c:5]([NH2:30])[n:6][cH:7][cH:8][cH:9]2)[CH2:2][CH2:3]1

Participants

11

Reactant 10

HCID 769Bicarbonate IonHCID 887MethanolHCID 923Sodium ion2×HCID 961HydroxideHCID 6228DimethylformamideHCID 6386tert-ButanolHCID 8471TriethylamineHCID 312751,4-DioxaneHCID 199401P,P-Diphenylphosphinic azideHCID 68687300Methyl 3-cyclopropylpyridine-2-carboxylate

Product 1

HCID 179624203-Cyclopropylpyridin-2-amine

Sources & evidence

ORD record
ord-8f88226ef055433682f584c22e635374
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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