Dimethylformamide → 2-Chloro-4-(2-chloro-4-difluoromethoxy-phenyl)-3-nitro-2,3-dihydro-pyridine

HRID 1563523Notes

Reaction equation

HRID 1563523 reaction equation
[Cl:6][c:7]1[c:8]([C:17]2=[CH:22][CH:21]=[N:20][C:19](=[O:23])[CH:18]2[N+:24](=[O:25])[O-:26])[cH:9][cH:10][c:11]([O:13][CH:14]([F:15])[F:16])[cH:12]1.[O:27]=[CH:28][N:29]([CH3:30])[CH3:31].[P:1]([Cl:2])([Cl:3])([Cl:4])=[O:5]>>[Cl:3][CH:19]1[CH:18]([N+:24](=[O:25])[O-:26])[C:17]([c:8]2[c:7]([Cl:6])[cH:12][c:11]([O:13][CH:14]([F:15])[F:16])[cH:10][cH:9]2)=[CH:22][CH:21]=[N:20]1

Participants

4

Reactant 3

HCID 6228DimethylformamideHCID 24813Phosphorus oxychlorideHCID 220521384-(2-chloro-4-difluoromethoxy-phenyl)3-nitro-3H-pyridin-2-one

Product 1

HCID 220520842-Chloro-4-(2-chloro-4-difluoromethoxy-phenyl)-3-nitro-2,3-dihydro-pyridine

Sources & evidence

ORD record
ord-9320aad358844c17a6a8c81c4caa8194
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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