Hydrochloric Acid → 1-Benzyl-4-(trifluoromethyl)piperidin-4-ol
Reaction equation
[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[N:8]1[CH2:9][CH2:10][C:11](=[O:14])[CH2:12][CH2:13]1.[CH2:42]1[O:43][CH2:44][CH2:45][CH2:46]1.[CH3:24][CH2:25][CH2:26][CH2:27][N+:28]([CH2:29][CH2:30][CH2:31][CH3:32])([CH2:33][CH2:34][CH2:35][CH3:36])[CH2:37][CH2:38][CH2:39][CH3:40].[ClH:41].[F-:23].[F:15][C:16]([F:17])([F:18])[Si:19]([CH3:20])([CH3:21])[CH3:22]>>[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[N:8]1[CH2:9][CH2:10][C:11]([OH:14])([C:16]([F:15])([F:17])[F:18])[CH2:12][CH2:13]1Participants
7
Sources & evidence
- ORD record
- ord-fb300f3943c2422d8dadc828ab33f1b9
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
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