Toluene → [4-Methoxy-2-(6-methoxy-3,4-dihydronaphthalen-2-yl)phenyl][4-(2-piperidin-1-ylethoxy)phenyl]methanone
Reaction equation
[Br:1][c:2]1[c:3]([C:10](=[O:11])[c:12]2[cH:13][cH:14][c:15]([O:18][CH2:19][CH2:20][N:21]3[CH2:22][CH2:23][CH2:24][CH2:25][CH2:26]3)[cH:16][cH:17]2)[cH:4][cH:5][c:6]([O:8][CH3:9])[cH:7]1.[CH3:27][O:28][c:29]1[cH:30][c:31]2[c:36]([cH:37][cH:38]1)[CH:35]=[C:34]([Sn:39]([CH3:40])([CH3:41])[CH3:42])[CH2:33][CH2:32]2.[CH3:43][CH2:44][O:45][C:46](=[O:47])[CH3:48].[CH3:49][c:50]1[cH:51][cH:52][cH:53][cH:54][cH:55]1.[Cu:133][I:134].[cH:56]1[cH:57][cH:58][c:59]([P:60]([Pd:61]([P:62]([c:63]2[cH:64][cH:65][cH:66][cH:67][cH:68]2)([c:69]2[cH:70][cH:71][cH:72][cH:73][cH:74]2)[c:75]2[cH:76][cH:77][cH:78][cH:79][cH:80]2)([P:81]([c:82]2[cH:83][cH:84][cH:85][cH:86][cH:87]2)([c:88]2[cH:89][cH:90][cH:91][cH:92][cH:93]2)[c:94]2[cH:95][cH:96][cH:97][cH:98][cH:99]2)[P:100]([c:101]2[cH:102][cH:103][cH:104][cH:105][cH:106]2)([c:107]2[cH:108][cH:109][cH:110][cH:111][cH:112]2)[c:113]2[cH:114][cH:115][cH:116][cH:117][cH:118]2)([c:119]2[cH:120][cH:121][cH:122][cH:123][cH:124]2)[c:125]2[cH:126][cH:127][cH:128][cH:129][cH:130]2)[cH:131][cH:132]1>>[c:2]1([C:34]2=[CH:35][c:36]3[c:31]([cH:30][c:29]([O:28][CH3:27])[cH:38][cH:37]3)[CH2:32][CH2:33]2)[c:3]([C:10](=[O:11])[c:12]2[cH:13][cH:14][c:15]([O:18][CH2:19][CH2:20][N:21]3[CH2:22][CH2:23][CH2:24][CH2:25][CH2:26]3)[cH:16][cH:17]2)[cH:4][cH:5][c:6]([O:8][CH3:9])[cH:7]1Participants
7
Reactant 6
HCID 1140Toluene
HCID 8857Ethyl Acetate
HCID 24350Copper(1+) iodide; Copper(I) iodide; Cuprous iodide; Cuprous iodide (CuI)
HCID 23087176(6-Methoxy-3,4-dihydronaphthalen-2-yl)trimethyltin
HCID 57933784(2-Bromo-4-methoxyphenyl)[4-(2-piperidin-1-ylethoxy)phenyl]methanone
HCID 178420554HCID 178420554, compoundProduct 1
Sources & evidence
- ORD record
- ord-e6e818656d1f47b3811010c2221372d8
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
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