Hydrochloric Acid → 7-[(4-Cyclopropylphenyl)acetyl]-2-(5-pyrimidin-2-yl-2,3-dihydro-1H-inden-1-yl)-2,7-diazaspiro[3.5]nonane

HRID 1564505Notes

Reaction equation

HRID 1564505 reaction equation
[CH3:1][CH2:2][N:3]([CH2:4][CH3:5])[CH2:6][CH3:7].[CH:34]1([c:37]2[cH:38][cH:39][c:40]([CH2:43][C:44](=[O:45])[OH:46])[cH:41][cH:42]2)[CH2:35][CH2:36]1.[Cl:71][CH2:72][Cl:73].[ClH:8].[ClH:9].[P-:47]([F:48])([F:49])([F:50])([F:51])([F:52])[F:53].[n:10]1[c:11](-[c:16]2[cH:17][c:18]3[c:22]([cH:23][cH:24]2)[CH:21]([N:25]2[CH2:26][C:27]4([CH2:28]2)[CH2:29][CH2:30][NH:31][CH2:32][CH2:33]4)[CH2:20][CH2:19]3)[n:12][cH:13][cH:14][cH:15]1.[n:54]1([O:55][C:56]([N:57]([CH3:58])[CH3:59])=[N+:60]([CH3:61])[CH3:62])[c:63]2[n:64][cH:65][cH:66][cH:67][c:68]2[n:69][n:70]1>>[n:10]1[c:11](-[c:16]2[cH:17][c:18]3[c:22]([cH:23][cH:24]2)[CH:21]([N:25]2[CH2:26][C:27]4([CH2:28]2)[CH2:29][CH2:30][N:31]([C:44]([CH2:43][c:40]2[cH:39][cH:38][c:37]([CH:34]5[CH2:35][CH2:36]5)[cH:42][cH:41]2)=[O:45])[CH2:32][CH2:33]4)[CH2:20][CH2:19]3)[n:12][cH:13][cH:14][cH:15]1

Participants

8

Reactant 7

HCID 313Hydrochloric Acid2×HCID 6344DichloromethaneHCID 8471TriethylamineHCID 9886HexafluorophosphateHCID 4641409(Dimethylamino)-N,N-dimethyl(3H-(1,2,3)triazolo(4,5-b)pyridin-3-yloxy)methaniminiumHCID 204905282-(4-Cyclopropylphenyl)acetic acidHCID 674119812-(5-pyrimidin-2-yl-2,3-dihydro-1H-inden-1-yl)-2,7-diazaspiro[3.5]nonane

Product 1

HCID 533902757-[(4-Cyclopropylphenyl)acetyl]-2-(5-pyrimidin-2-yl-2,3-dihydro-1H-inden-1-yl)-2,7-diazaspiro[3.5]nonane

Sources & evidence

ORD record
ord-cb66bb8988ad4c578fb282bb15956225
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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