Diisopropyl Ether → 1-(4-(6-(4-(Benzyloxy)phenylamino)pyrimidin-4-yloxy)-3-fluorophenyl)-3-(2-(4-fluorophenyl)acetyl)urea
Reaction equation
[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[O:8][c:9]1[cH:10][cH:11][c:12]([NH:15][c:16]2[cH:17][c:18]([O:22][c:23]3[c:24]([F:43])[cH:25][c:26]([NH:29][C:30](=[O:31])[CH2:32][C:33]([NH:34][c:35]4[cH:36][cH:37][c:38]([F:39])[cH:40][cH:41]4)=[O:42])[cH:27][cH:28]3)[n:19][cH:20][n:21]2)[cH:13][cH:14]1.[CH2:64]1[O:65][CH2:66][CH2:67][CH2:68]1.[CH:57]([O:58][CH:59]([CH3:60])[CH3:61])([CH3:62])[CH3:63].[F:44][c:45]1[cH:46][cH:47][c:48]([CH2:51][C:52](=[O:53])[N:54]=[C:55]=[O:56])[cH:49][cH:50]1>>[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[O:8][c:9]1[cH:10][cH:11][c:12]([NH:15][c:16]2[cH:17][c:18]([O:22][c:23]3[c:24]([F:43])[cH:25][c:26]([NH:29][C:55]([NH:54][C:52]([CH2:51][c:48]4[cH:47][cH:46][c:45]([F:44])[cH:50][cH:49]4)=[O:53])=[O:56])[cH:27][cH:28]3)[n:19][cH:20][n:21]2)[cH:13][cH:14]1Participants
5
Reactant 4
Product 1
Sources & evidence
- ORD record
- ord-0c3f9f6dae0943e5a64d40b768a5bada
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
Loading…