Dimethylformamide → 5-{2-Amino-6-[3-(3-tert-butoxycarbonylaminopropoxy)phenylsulfanyl]pyrimidin-4-yl}-2-methoxy-4-methylbenzoic acid methyl ester
Reaction equation
[C:29](=[O:30])([O-:31])[O-:32].[C:40]([CH3:41])([CH3:42])([CH3:43])[O:44][C:45]([NH:46][CH2:47][CH2:48][CH2:49][Br:50])=[O:51].[CH3:1][O:2][C:3]([c:4]1[c:5]([O:26][CH3:27])[cH:6][c:7]([CH3:25])[c:8](-[c:10]2[n:11][c:12]([NH2:24])[n:13][c:14]([S:16][c:17]3[cH:18][c:19]([OH:23])[cH:20][cH:21][cH:22]3)[cH:15]2)[cH:9]1)=[O:28].[CH3:35][N:36]([CH3:37])[CH:38]=[O:39].[CH3:52][CH2:53][O:54][C:55](=[O:56])[CH3:57].[Cs+:33].[Cs+:34]>>[CH3:1][O:2][C:3]([c:4]1[c:5]([O:26][CH3:27])[cH:6][c:7]([CH3:25])[c:8](-[c:10]2[n:11][c:12]([NH2:24])[n:13][c:14]([S:16][c:17]3[cH:18][c:19]([O:23][CH2:49][CH2:48][CH2:47][NH:46][C:45]([O:44][C:40]([CH3:41])([CH3:42])[CH3:43])=[O:51])[cH:20][cH:21][cH:22]3)[cH:15]2)[cH:9]1)=[O:28]Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-d8bdc0bba56447ecaa429fb2876c5519
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
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