Triethylamine → (+/-)-5-Amino-4'-chloro-1,3-dihydrospiro[indene-2,5'-pyrrolo[2,3-d]pyrimidin]-6'(7'H)-one

HRID 1565231Notes

Reaction equation

HRID 1565231 reaction equation
[CH3:23][CH2:24][N:25]([CH2:26][CH3:27])[CH2:28][CH3:29].[CH3:32][CH2:33][O:34][C:35]([CH3:36])=[O:37].[Cl:1][c:2]1[c:3]2[c:4]([n:5][cH:6][n:7]1)[NH:8][C:9](=[O:22])[C:10]21[CH2:11][c:12]2[cH:13][cH:14][c:15]([N+:19]([O-:20])=[O:21])[cH:16][c:17]2[CH2:18]1.[H:30][H:31]>>[Cl:1][c:2]1[c:3]2[c:4]([n:5][cH:6][n:7]1)[NH:8][C:9](=[O:22])[C:10]21[CH2:11][c:12]2[cH:13][cH:14][c:15]([NH2:19])[cH:16][c:17]2[CH2:18]1

Participants

5

Reactant 4

HCID 8471TriethylamineHCID 8857Ethyl AcetateHCID 59166727HCID 59166727, compoundHCID 178418361HCID 178418361, compound

Product 1

HCID 59166731(+/-)-5-Amino-4'-chloro-1,3-dihydrospiro[indene-2,5'-pyrrolo[2,3-d]pyrimidin]-6'(7'H)-one

Sources & evidence

ORD record
ord-e14e6305b15641f0a570077716df3a5b
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

Loading…