Tetrahydrofuran → 2-[4-[2-(3-Hydroxypyrrolidin-1-yl)pyrimidin-4-yl]-3-(3-methoxy-5-methylphenyl)pyrazol-1-yl]acetonitrile
Reaction equation
[CH3:1][S:2](=[O:3])(=[O:4])[c:5]1[n:6][cH:7][cH:8][c:9](-[c:11]2[c:12](-[c:19]3[cH:20][c:21]([O:26][CH3:27])[cH:22][c:23]([CH3:25])[cH:24]3)[n:13][n:14]([CH2:16][C:17]#[N:18])[cH:15]2)[n:10]1.[CH:34]([N:35]([CH2:36][CH3:37])[CH:38]([CH3:39])[CH3:40])([CH3:41])[CH3:42].[O:43]1[CH2:44][CH2:45][CH2:46][CH2:47]1.[OH:28][CH:29]1[CH2:30][NH:31][CH2:32][CH2:33]1>>[c:5]1([N:31]2[CH2:30][CH:29]([OH:28])[CH2:33][CH2:32]2)[n:6][cH:7][cH:8][c:9](-[c:11]2[c:12](-[c:19]3[cH:20][c:21]([O:26][CH3:27])[cH:22][c:23]([CH3:25])[cH:24]3)[n:13][n:14]([CH2:16][C:17]#[N:18])[cH:15]2)[n:10]1Participants
5
Reactant 4
Product 1
Sources & evidence
- ORD record
- ord-af3644a2abfc446c9563aefd094fb63f
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
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