Tetrahydrofuran → 2-Chloro-4-(2-fluoroethoxy)-5-(2,3-difluoro-6-methoxybenzyloxy)-1-nitrobenzene

HRID 1566158Notes

Reaction equation

HRID 1566158 reaction equation
[Cl:1][c:2]1[c:3]([N+:21](=[O:22])[O-:23])[cH:4][c:5]([O:9][CH2:10][c:11]2[c:12]([F:20])[c:13]([F:19])[cH:14][cH:15][c:16]2[O:17][CH3:18])[c:6]([OH:8])[cH:7]1.[F:24][CH2:25][CH2:26][OH:27].[O:47]=[C:48]([O:49][CH:50]([CH3:51])[CH3:52])[N:53]=[N:54][C:55]([O:56][CH:57]([CH3:58])[CH3:59])=[O:60].[O:61]1[CH2:62][CH2:63][CH2:64][CH2:65]1.[c:28]1([P:29]([c:30]2[cH:31][cH:32][cH:33][cH:34][cH:35]2)[c:36]2[cH:37][cH:38][cH:39][cH:40][cH:41]2)[cH:42][cH:43][cH:44][cH:45][cH:46]1>>[Cl:1][c:2]1[c:3]([N+:21](=[O:22])[O-:23])[cH:4][c:5]([O:9][CH2:10][c:11]2[c:12]([F:20])[c:13]([F:19])[cH:14][cH:15][c:16]2[O:17][CH3:18])[c:6]([O:8][CH2:26][CH2:25][F:24])[cH:7]1

Participants

6

Reactant 5

HCID 8028TetrahydrofuranHCID 97372-FluoroethanolHCID 11776TriphenylphosphineHCID 75555Diisopropyl diazene-1,2-dicarboxylateHCID 593098495-Chloro-2-(2,3-difluoro-6-methoxybenzyloxy)-4-nitrophenol

Product 1

HCID 866412772-Chloro-4-(2-fluoroethoxy)-5-(2,3-difluoro-6-methoxybenzyloxy)-1-nitrobenzene

Sources & evidence

ORD record
ord-34ad299166c34e09a9eb69fd24f3302b
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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