1-Chloro-4-(chloromethyl)benzene → 1-tert-Butyl 4-ethyl 4-[(4-chlorophenyl)methyl]piperidine-1,4-dicarboxylate
Reaction equation
[CH2:1]([CH3:2])[O:3][C:4]([CH:5]1[CH2:6][CH2:7][N:8]([C:11](=[O:12])[O:13][C:14]([CH3:15])([CH3:16])[CH3:17])[CH2:9][CH2:10]1)=[O:18].[CH3:19][Si:20]([N-:21][Si:22]([CH3:23])([CH3:24])[CH3:25])([CH3:26])[CH3:27].[Cl:29][c:30]1[cH:31][cH:32][c:33]([CH2:34][Cl:35])[cH:36][cH:37]1.[Li+:28].[O:38]1[CH2:39][CH2:40][CH2:41][CH2:42]1>>[CH2:1]([CH3:2])[O:3][C:4]([C:5]1([CH2:34][c:33]2[cH:32][cH:31][c:30]([Cl:29])[cH:37][cH:36]2)[CH2:6][CH2:7][N:8]([C:11](=[O:12])[O:13][C:14]([CH3:15])([CH3:16])[CH3:17])[CH2:9][CH2:10]1)=[O:18]Participants
6
Sources & evidence
- ORD record
- ord-547e9e90150e468589c283157cd5c0ff
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
Loading…