Dimethylformamide → 5-chloro-4-(3-(4-ethoxypiperidine-1-carbonyl)-5-fluorobenzyl)phthalazin-1(2H)-one

HRID 1566801Notes

Reaction equation

HRID 1566801 reaction equation
[CH2:24]([CH3:25])[O:26][CH:27]1[CH2:28][CH2:29][NH:30][CH2:31][CH2:32]1.[CH:33]([N:34]([CH2:35][CH3:36])[CH:37]([CH3:38])[CH3:39])([CH3:40])[CH3:41].[Cl:1][c:2]1[cH:3][cH:4][cH:5][c:6]2[c:7](=[O:23])[nH:8][n:9][c:10]([CH2:12][c:13]3[cH:14][c:15]([C:16](=[O:17])[OH:18])[cH:19][c:20]([F:22])[cH:21]3)[c:11]12.[O:42]=[CH:43][N:44]([CH3:45])[CH3:46]>>[Cl:1][c:2]1[cH:3][cH:4][cH:5][c:6]2[c:7](=[O:23])[nH:8][n:9][c:10]([CH2:12][c:13]3[cH:14][c:15]([C:16](=[O:17])[N:30]4[CH2:29][CH2:28][CH:27]([O:26][CH2:24][CH3:25])[CH2:32][CH2:31]4)[cH:19][c:20]([F:22])[cH:21]3)[c:11]12

Participants

5

Reactant 4

HCID 6228DimethylformamideHCID 81531DiisopropylethylamineHCID 115065194-EthoxypiperidineHCID 577917753-((8-Chloro-4-oxo-3,4-dihydrophthalazin-1-yl)methyl)-5-fluorobenzoic acid

Product 1

HCID 577917815-chloro-4-(3-(4-ethoxypiperidine-1-carbonyl)-5-fluorobenzyl)phthalazin-1(2H)-one

Sources & evidence

ORD record
ord-da575f438af54f06881eac7eb94ba4ee
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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