Tetrahydrofuran → alpha-Ethyl-alpha-(3-chlorophenyl)-4-[2-(dimethylamino)-ethoxy]-benzylalcohol
Reaction equation
[CH3:2][N:3]([CH2:4][CH2:5][O:6][c:7]1[cH:8][cH:9][c:10]([Br:13])[cH:11][cH:12]1)[CH3:14].[Cl:15][c:16]1[cH:17][c:18]([C:22]([CH2:23][CH3:24])=[O:25])[cH:19][cH:20][cH:21]1.[Mg:1].[O:26]1[CH2:27][CH2:28][CH2:29][CH2:30]1>>[CH3:2][N:3]([CH2:4][CH2:5][O:6][c:7]1[cH:8][cH:9][c:10]([C:22]([c:18]2[cH:17][c:16]([Cl:15])[cH:21][cH:20][cH:19]2)([CH2:23][CH3:24])[OH:25])[cH:11][cH:12]1)[CH3:14]Participants
5
Sources & evidence
- ORD record
- ord-3e83c6d84fc14e3ab913c973eb424414
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
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