Hydrochloric Acid → Bcl-xL antagonist 2

HRID 1568264Notes

Reaction equation

HRID 1568264 reaction equation
[CH2:35]1[O:36][CH2:37][CH2:38][CH2:39]1.[CH3:40][OH:41].[ClH:34].[Na+:33].[OH-:32].[s:1]1[c:2]([NH:10][C:11](=[O:12])[c:13]2[cH:14][cH:15][cH:16][c:17]3[c:22]2[CH2:21][N:20]([c:23]2[s:24][cH:25][c:26]([C:28](=[O:29])[O:30][CH3:31])[n:27]2)[CH2:19][CH2:18]3)[n:3][c:4]2[c:5]1[cH:6][cH:7][cH:8][cH:9]2>>[s:1]1[c:2]([NH:10][C:11](=[O:12])[c:13]2[cH:14][cH:15][cH:16][c:17]3[c:22]2[CH2:21][N:20]([c:23]2[s:24][cH:25][c:26]([C:28](=[O:29])[OH:30])[n:27]2)[CH2:19][CH2:18]3)[n:3][c:4]2[c:5]1[cH:6][cH:7][cH:8][cH:9]2

Participants

7

Reactant 6

HCID 313Hydrochloric AcidHCID 887MethanolHCID 923Sodium ionHCID 961HydroxideHCID 8028TetrahydrofuranHCID 59447460methyl 2-(8-(benzo[d]thiazol-2-ylcarbamoyl)-3,4-dihydroisoquinolin-2(1H)-yl)thiazole-4-carboxylate

Product 1

HCID 46836567Bcl-xL antagonist 2

Sources & evidence

ORD record
ord-8f125af621c04897aca1246616715b53
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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