Tetrahydrofuran → [2-(4-Fluoro-benzyl)-6-methoxy-naphthalen-1-yl]-[4-(2-piperidin-1-yl-ethoxy)-phenyl]-methanol
Reaction equation
[Al+3:2].[CH2:44]1[O:45][CH2:46][CH2:47][CH2:48]1.[F:7][c:8]1[cH:9][cH:10][c:11]([CH2:12][c:13]2[c:14]([C:25](=[O:26])[c:27]3[cH:28][cH:29][c:30]([O:33][CH2:34][CH2:35][N:36]4[CH2:37][CH2:38][CH2:39][CH2:40][CH2:41]4)[cH:31][cH:32]3)[c:15]3[cH:16][cH:17][c:18]([O:23][CH3:24])[cH:19][c:20]3[cH:21][cH:22]2)[cH:42][cH:43]1.[H-:1].[H-:4].[H-:5].[H-:6].[Li+:3]>>[F:7][c:8]1[cH:9][cH:10][c:11]([CH2:12][c:13]2[c:14]([CH:25]([OH:26])[c:27]3[cH:28][cH:29][c:30]([O:33][CH2:34][CH2:35][N:36]4[CH2:37][CH2:38][CH2:39][CH2:40][CH2:41]4)[cH:31][cH:32]3)[c:15]3[cH:16][cH:17][c:18]([O:23][CH3:24])[cH:19][c:20]3[cH:21][cH:22]2)[cH:42][cH:43]1Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-e873f7cecc614c7fa9f4a3e0959500e7
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
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