Dichloromethane → 3-Cyano-3-(4-fluorophenyl)cyclobutan-1-yl t-butyldimethylsilyl ether

HRID 1568777Notes

Reaction equation

HRID 1568777 reaction equation
[C:1](#[N:2])[C:3]1([c:8]2[cH:9][cH:10][c:11]([F:14])[cH:12][cH:13]2)[CH2:4][CH:5]([OH:7])[CH2:6]1.[Cl:38][CH2:39][Cl:40].[F:23][C:24]([F:25])([F:26])[S:27]([O:28][Si:29]([CH3:30])([CH3:31])[C:32]([CH3:33])([CH3:34])[CH3:35])(=[O:36])=[O:37].[n:15]1[c:16]([CH3:17])[cH:18][cH:19][cH:20][c:21]1[CH3:22]>>[C:1](#[N:2])[C:3]1([c:8]2[cH:9][cH:10][c:11]([F:14])[cH:12][cH:13]2)[CH2:4][CH:5]([O:7][Si:29]([CH3:30])([CH3:31])[C:32]([CH3:33])([CH3:34])[CH3:35])[CH2:6]1

Participants

5

Reactant 4

HCID 6344DichloromethaneHCID 79372,6-LutidineHCID 123564tert-Butyldimethylsilyl trifluoromethanesulphonateHCID 583809881202008-97-6

Product 1

HCID 583809273-Cyano-3-(4-fluorophenyl)cyclobutan-1-yl t-butyldimethylsilyl ether

Sources & evidence

ORD record
ord-71d781e69b594ef386418f518c5bace4
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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