Toluene → 1-Benzyl-N-(3,4-difluorobenzyl)-6-(3,4-dihydro-2H-pyrrol-5-ylamino)-5-fluoro-2-isopropyl-1H-indole-3-carboxamide
Reaction equation
[CH3:45][c:46]1[cH:47][cH:48][cH:49][cH:50][cH:51]1.[CH3:52][CH2:53][O:54][C:55]([CH3:56])=[O:57].[NH2:12][c:13]1[c:14]([F:44])[cH:15][c:16]2[c:17]([C:32](=[O:33])[NH:34][CH2:35][c:36]3[cH:37][c:38]([F:43])[c:39]([F:42])[cH:40][cH:41]3)[c:18]([CH:29]([CH3:30])[CH3:31])[n:19]([CH2:22][c:23]3[cH:24][cH:25][cH:26][cH:27][cH:28]3)[c:20]2[cH:21]1.[NH:1]1[C:2](=[O:6])[CH2:3][CH2:4][CH2:5]1.[P:7]([Cl:8])([Cl:9])([Cl:10])=[O:11]>>[N:1]1=[C:2]([NH:12][c:13]2[c:14]([F:44])[cH:15][c:16]3[c:17]([C:32](=[O:33])[NH:34][CH2:35][c:36]4[cH:37][c:38]([F:43])[c:39]([F:42])[cH:40][cH:41]4)[c:18]([CH:29]([CH3:30])[CH3:31])[n:19]([CH2:22][c:23]4[cH:24][cH:25][cH:26][cH:27][cH:28]4)[c:20]3[cH:21]2)[CH2:3][CH2:4][CH2:5]1Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-9e62aaa4209e4af89a65b7d60d1cb399
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
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