Water → 1-[2-Amino-3-chloro-4-(2,2-dimethoxy-ethoxy)-phenyl]-ethanone

HRID 1569068Notes

Reaction equation

HRID 1569068 reaction equation
[C:13](=[O:14])([O-:15])[O-:16].[CH3:19][O:20][CH:21]([CH2:22][Br:23])[O:24][CH3:25].[CH3:26][CH2:27][O:28][C:29]([CH3:30])=[O:31].[Cs+:17].[Cs+:18].[NH2:1][c:2]1[c:3]([C:10]([CH3:11])=[O:12])[cH:4][cH:5][c:6]([OH:9])[c:7]1[Cl:8].[O:32]=[CH:33][N:34]([CH3:35])[CH3:36].[OH2:37]>>[NH2:1][c:2]1[c:3]([C:10]([CH3:11])=[O:12])[cH:4][cH:5][c:6]([O:9][CH2:22][CH:21]([O:20][CH3:19])[O:24][CH3:25])[c:7]1[Cl:8]

Participants

8

Reactant 7

HCID 962WaterHCID 6228DimethylformamideHCID 8857Ethyl AcetateHCID 19660Carbonate IonHCID 816722-Bromo-1,1-dimethoxyethaneHCID 104967Cesium cation2×HCID 574451951-(2-Amino-3-chloro-4-hydroxy-phenyl)-ethanone

Product 1

HCID 574451961-[2-Amino-3-chloro-4-(2,2-dimethoxy-ethoxy)-phenyl]-ethanone

Sources & evidence

ORD record
ord-d0ac8291ba2b43c0bd0772da9c259b18
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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