Methanol → 3-(4-Nitro-benzyl)-oxazolidin-2-one

HRID 1569402Notes

Reaction equation

HRID 1569402 reaction equation
[Br:9][CH2:10][c:11]1[cH:12][cH:13][c:14]([N+:17](=[O:18])[O-:19])[cH:15][cH:16]1.[CH2:22]1[O:23][CH2:24][CH2:25][CH2:26]1.[CH2:27]1[O:28][CH2:29][CH2:30][CH2:31]1.[CH3:20][OH:21].[H-:2].[Na+:1].[O:32]=[CH:33][N:34]([CH3:35])[CH3:36].[O:3]1[C:4](=[O:8])[NH:5][CH2:6][CH2:7]1.[OH2:37]>>[O:3]1[C:4](=[O:8])[N:5]([CH2:10][c:11]2[cH:12][cH:13][c:14]([N+:17](=[O:18])[O-:19])[cH:15][cH:16]2)[CH2:6][CH2:7]1

Participants

9

Reactant 8

HCID 887MethanolHCID 923Sodium ionHCID 962WaterHCID 6228DimethylformamideHCID 8028Tetrahydrofuran2×HCID 660114-Nitrobenzyl bromideHCID 739492-OxazolidinoneHCID 166653Hydride

Product 1

HCID 666364983-(4-Nitro-benzyl)-oxazolidin-2-one

Sources & evidence

ORD record
ord-2e3858d950b64c91ab967d5cbc0aae85
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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