Carbamate → Piperidine

HRID 1571461Notes

Reaction equation

HRID 1571461 reaction equation
[CH2:1]1[CH2:2][CH2:3][NH:4][CH2:5][CH2:6]1.[CH3:36][c:37]1[cH:38][cH:39][cH:40][cH:41][cH:42]1.[NH2:28][C:29]([O-:30])=[O:31].[O:25]=[C:26]=[O:27].[S:32]([Cl:33])([Cl:34])=[O:35].[cH:13]1[cH:14][cH:15][c:16](-[c:17]2[cH:18][cH:19][cH:20][cH:21][cH:22]2)[cH:23][cH:24]1.[cH:7]1[cH:8][cH:9][n:10][cH:11][cH:12]1>>[CH2:1]1[CH2:2][CH2:3][NH:4][CH2:5][CH2:6]1.[NH2:28][C:29](=[O:31])[Cl:34]

Participants

9

Reactant 7

HCID 276CarbamateHCID 280Carbon DioxideHCID 1049PyridineHCID 1140TolueneHCID 7095BiphenylHCID 8082PiperidineHCID 24386Thionyl Chloride

Product 2

HCID 8082PiperidineHCID 68048Carbamic chloride

Sources & evidence

ORD record
ord-e673f8994abe4e9fbf79658c54b5d4ec
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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