Bromide ion → 4-[3-fluoro-4-(methylsulfanyl)phenyl]-5-(tetrahydro-2H-pyran-4-yl)pent-1-en-3-one
Reaction equation
[Br-:24].[CH:25](=[CH2:26])[Mg+:27].[ClH:28].[F:1][c:2]1[cH:3][c:4]([CH:10]([C:11](=[O:12])[N:13]([O:14][CH3:15])[CH3:16])[CH2:17][CH:18]2[CH2:19][CH2:20][O:21][CH2:22][CH2:23]2)[cH:5][cH:6][c:7]1[S:8][CH3:9].[O:29]1[CH2:30][CH2:31][CH2:32][CH2:33]1>>[F:1][c:2]1[cH:3][c:4]([CH:10]([C:11](=[O:12])[CH:25]=[CH2:26])[CH2:17][CH:18]2[CH2:19][CH2:20][O:21][CH2:22][CH2:23]2)[cH:5][cH:6][c:7]1[S:8][CH3:9]Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-3bb10465bd8e4369b9ff059ca4e63461
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
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