Hydroxide → tert-butyl 4-(7-hydroxy-5-methyl-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-yl)-3-methylpiperazine-1-carboxylate

HRID 1572333Notes

Reaction equation

HRID 1572333 reaction equation
[C:1](=[O:2])([CH3:3])[O:4][CH:5]1[CH2:6][CH:7]([CH3:28])[c:8]2[c:9]1[n:10][cH:11][n:12][c:13]2[N:14]1[CH:15]([CH3:27])[CH2:16][N:17]([C:20](=[O:21])[O:22][C:23]([CH3:24])([CH3:25])[CH3:26])[CH2:18][CH2:19]1.[CH2:31]1[O:32][CH2:33][CH2:34][CH2:35]1.[Li+:30].[OH-:29]>>[OH:4][CH:5]1[CH2:6][CH:7]([CH3:28])[c:8]2[c:9]1[n:10][cH:11][n:12][c:13]2[N:14]1[CH:15]([CH3:27])[CH2:16][N:17]([C:20](=[O:21])[O:22][C:23]([CH3:24])([CH3:25])[CH3:26])[CH2:18][CH2:19]1

Participants

5

Reactant 4

HCID 961HydroxideHCID 8028TetrahydrofuranHCID 28486Lithium ionHCID 67143529tert-butyl 4-(7-acetyloxy-5-methyl-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-yl)-3-methylpiperazine-1-carboxylate

Product 1

HCID 72353678tert-butyl 4-(7-hydroxy-5-methyl-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-yl)-3-methylpiperazine-1-carboxylate

Sources & evidence

ORD record
ord-dff6a137f22c4f11b831112ce828cca3
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

Loading…