Potassium Cation → 5-fluoro-3-(4-methoxyphenyl)-8-propoxy-1H-quinolin-4-one
Reaction equation
[C:10](=[O:11])([O-:12])[O-:13].[C:16](=[O:17])([OH:18])[CH:19]([CH2:20][NH-:21])[Cl:22].[CH3:1][N:2]1[CH2:3][CH2:4][NH:5][CH2:6][CH2:7]1.[F:23][c:24]1[c:25]2[c:26](=[O:46])[c:27](-[c:38]3[cH:39][cH:40][c:41]([O:44][CH3:45])[cH:42][cH:43]3)[cH:28][nH:29][c:30]2[c:31]([O:34][CH2:35][CH2:36][CH3:37])[cH:32][cH:33]1.[I-:9].[K+:14].[K+:15].[Na+:8].[O:48]=[CH:49][N:50]([CH3:51])[CH3:52].[OH2:47]>>[CH3:1][N:2]1[CH2:3][CH2:4][N:5]([CH:19]([C:16](=[O:17])[OH:18])[CH2:20][NH-:21])[CH2:6][CH2:7]1.[F:23][c:24]1[c:25]2[c:26](=[O:46])[c:27](-[c:38]3[cH:39][cH:40][c:41]([O:44][CH3:45])[cH:42][cH:43]3)[cH:28][nH:29][c:30]2[c:31]([O:34][CH2:35][CH2:36][CH3:37])[cH:32][cH:33]1Participants
11
Reactant 9
Product 2
Sources & evidence
- ORD record
- ord-b163a28ca3074a86bfedff8ddfa6effc
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
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