Diethyl Ether → 2-((1-(4-fluorophenyl)-1H-indazol-5-yl)(phenyl)methyl)butan-1-amine

HRID 1572738Notes

Reaction equation

HRID 1572738 reaction equation
[Al+3:31].[CH2:41]1[O:42][CH2:43][CH2:44][CH2:45]1.[CH3:36][CH2:37][O:38][CH2:39][CH3:40].[F:1][c:2]1[cH:3][cH:4][c:5](-[n:8]2[n:9][cH:10][c:11]3[cH:12][c:13]([CH:17]([CH:18]([C:19](=[O:20])[NH2:21])[CH2:22][CH3:23])[c:24]4[cH:25][cH:26][cH:27][cH:28][cH:29]4)[cH:14][cH:15][c:16]23)[cH:6][cH:7]1.[H-:30].[H-:33].[H-:34].[H-:35].[Li+:32]>>[F:1][c:2]1[cH:3][cH:4][c:5](-[n:8]2[n:9][cH:10][c:11]3[cH:12][c:13]([CH:17]([CH:18]([CH2:19][NH2:21])[CH2:22][CH3:23])[c:24]4[cH:25][cH:26][cH:27][cH:28][cH:29]4)[cH:14][cH:15][c:16]23)[cH:6][cH:7]1

Participants

7

Reactant 6

HCID 3283Diethyl EtherHCID 8028TetrahydrofuranHCID 28486Lithium ionHCID 104727Aluminum CationHCID 166653Hydride4×HCID 687066063-(1-(4-fluorophenyl)-1H-indazol-5-yl)-2-ethyl-3-phenylpropanamide

Product 1

HCID 687056882-((1-(4-fluorophenyl)-1H-indazol-5-yl)(phenyl)methyl)butan-1-amine

Sources & evidence

ORD record
ord-f39c552125c042d0a94393612f330286
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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