4-Chlorobenzaldehyde → 1-(4-Chlorophenyl)-2-[3-(2,6-difluorophenyl)-[1,2,4]triazin-6-yl]-ethanol
Reaction equation
[CH2:1]([Li:2])[CH2:3][CH2:4][CH3:5].[CH:6]([NH:7][CH:8]([CH3:9])[CH3:10])([CH3:11])[CH3:12].[Cl:28][c:29]1[cH:30][cH:31][c:32]([CH:33]=[O:34])[cH:35][cH:36]1.[F:13][c:14]1[c:15](-[c:21]2[n:22][n:23][c:24]([CH3:27])[cH:25][n:26]2)[c:16]([F:20])[cH:17][cH:18][cH:19]1.[O:37]1[CH2:38][CH2:39][CH2:40][CH2:41]1>>[F:13][c:14]1[c:15](-[c:21]2[n:22][n:23][c:24]([CH2:27][CH:33]([c:32]3[cH:31][cH:30][c:29]([Cl:28])[cH:36][cH:35]3)[OH:34])[cH:25][n:26]2)[c:16]([F:20])[cH:17][cH:18][cH:19]1Participants
6
Sources & evidence
- ORD record
- ord-68c62e81109148998b7029e85e524e5a
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
Loading…