Dichloromethane → 5-(1-(Tert-butyldimethylsilyloxy)propan-2-yl)-2-fluoropyridine
Reaction equation
[CH:27]([N:28]([CH2:29][CH3:30])[CH:31]([CH3:32])[CH3:33])([CH3:34])[CH3:35].[Cl:36][CH2:37][Cl:38].[F:16][c:17]1[cH:18][cH:19][c:20]([CH:23]([CH2:24][OH:25])[CH3:26])[cH:21][n:22]1.[F:1][C:2]([F:3])([F:4])[S:5]([O:6][Si:7]([CH3:8])([CH3:9])[C:10]([CH3:11])([CH3:12])[CH3:13])(=[O:14])=[O:15]>>[O:6]([Si:7]([CH3:8])([CH3:9])[C:10]([CH3:11])([CH3:12])[CH3:13])[CH2:24][CH:23]([c:20]1[cH:19][cH:18][c:17]([F:16])[n:22][cH:21]1)[CH3:26]Participants
5
Sources & evidence
- ORD record
- ord-700d0c66a7ba49ceae02876686ae0f9a
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
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