Acetate → Methyl 2-fluoro-4-phenylbenzoate

HRID 1573783Notes

Reaction equation

HRID 1573783 reaction equation
[Br:1][c:2]1[cH:3][c:4]([F:12])[c:5]([C:6](=[O:7])[O:8][CH3:9])[cH:10][cH:11]1.[Cs+:23].[F-:22].[O-:30][C:31]([CH3:32])=[O:33].[O-:34][C:35]([CH3:36])=[O:37].[O:24]=[CH:25][N:26]([CH3:27])[CH3:28].[OH2:38].[OH:13][B:14]([OH:15])[c:16]1[cH:17][cH:18][cH:19][cH:20][cH:21]1.[Pd+2:29]>>[c:2]1(-[c:16]2[cH:17][cH:18][cH:19][cH:20][cH:21]2)[cH:3][c:4]([F:12])[c:5]([C:6](=[O:7])[O:8][CH3:9])[cH:10][cH:11]1

Participants

9

Reactant 8

HCID 175Acetate2×HCID 962WaterHCID 6228DimethylformamideHCID 28179Fluoride IonHCID 66827Phenylboronic AcidHCID 104967Cesium cationHCID 105144Allyl(1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene)chloropalladium(II)HCID 113453114-Bromo-2-fluoro-benzoic acid methyl ester

Product 1

HCID 69129634Methyl 2-fluoro-4-phenylbenzoate

Sources & evidence

ORD record
ord-79d0f224dabd4f41a9894667f4e2068f
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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