Triethylamine → Tert-butyl 4-bromo-1-oxoisoindoline-2-carboxylate

HRID 157382Notes

Reaction equation

HRID 157382 reaction equation
[Br:1][c:2]1[c:3]2[c:7]([cH:8][cH:9][cH:10]1)[C:6](=[O:11])[NH:5][CH2:4]2.[C:12](=[O:13])([O:14][C:15]([CH3:16])([CH3:17])[CH3:18])[O:19][C:20]([O-:21])=[O:22].[CH3:23][CH2:24][N:25]([CH2:26][CH3:27])[CH2:28][CH3:29].[CH3:30][N:31]([c:32]1[cH:33][cH:34][n:35][cH:36][cH:37]1)[CH3:38]>>[Br:1][c:2]1[c:3]2[c:7]([cH:8][cH:9][cH:10]1)[C:6](=[O:11])[N:5]([C:12](=[O:13])[O:14][C:15]([CH3:16])([CH3:17])[CH3:18])[CH2:4]2

Participants

5

Reactant 4

HCID 8471TriethylamineHCID 142844-(Dimethylamino)pyridineHCID 219075094-Bromoisoindolin-1-oneHCID 22064466Tert-butyldicarbonate

Product 1

HCID 86593478Tert-butyl 4-bromo-1-oxoisoindoline-2-carboxylate

Sources & evidence

ORD record
ord-2e78abc3b09b423087494f09acff1871
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

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