Diethyl Ether → 4-[2-(Azetidin-1-yl)ethyl]piperazine-1-carboxylic acid [4-(4-{3-[2-(4-fluorophenyl)acetyl]ureido}phenoxy)pyridin-2-yl]amide
Reaction equation
[CH3:43][N:44]([CH3:45])[CH:46]=[O:47].[CH3:48][CH2:49][O:50][C:51](=[O:52])[CH3:53].[CH3:54][CH2:55][O:56][CH2:57][CH3:58].[CH3:59][CH2:60][CH2:61][CH2:62][CH2:63][CH3:64].[F:30][c:31]1[cH:32][cH:33][c:34]([CH2:37][C:38](=[O:39])[N:40]=[C:41]=[O:42])[cH:35][cH:36]1.[NH2:1][c:2]1[cH:3][cH:4][c:5]([O:6][c:7]2[cH:8][c:9]([NH:13][C:14](=[O:15])[N:16]3[CH2:17][CH2:18][N:19]([CH2:22][CH2:23][N:24]4[CH2:25][CH2:26][CH2:27]4)[CH2:20][CH2:21]3)[n:10][cH:11][cH:12]2)[cH:28][cH:29]1>>[NH:1]([c:2]1[cH:3][cH:4][c:5]([O:6][c:7]2[cH:8][c:9]([NH:13][C:14](=[O:15])[N:16]3[CH2:17][CH2:18][N:19]([CH2:22][CH2:23][N:24]4[CH2:25][CH2:26][CH2:27]4)[CH2:20][CH2:21]3)[n:10][cH:11][cH:12]2)[cH:28][cH:29]1)[C:41]([NH:40][C:38]([CH2:37][c:34]1[cH:33][cH:32][c:31]([F:30])[cH:36][cH:35]1)=[O:39])=[O:42]Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-1c78afcb25bc4ff59e16950a45cbc29d
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
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