1,2-Dichloroethane → 2-amino-5-[4-(difluoromethoxy)phenyl]-3-methyl-5-[3-(pyrrolidin-1-ylmethyl)phenyl]-3,5-dihydro-4H-imidazol-4-one
Reaction equation
[C:32]([O:33][BH-:34]([O:35][C:36](=[O:37])[CH3:38])[O:39][C:40](=[O:41])[CH3:42])(=[O:43])[CH3:44].[CH2:27]1[CH2:28][CH2:29][NH:30][CH2:31]1.[CH3:52][C:53](=[O:54])[OH:55].[Cl:48][CH2:49][CH2:50][Cl:51].[NH2:1][C:2]1=[N:6][C:5]([c:7]2[cH:8][cH:9][c:10]([O:13][CH:14]([F:15])[F:16])[cH:11][cH:12]2)([c:17]2[cH:18][c:19]([CH:20]=[O:21])[cH:22][cH:23][cH:24]2)[C:4](=[O:25])[N:3]1[CH3:26].[Na+:45].[Na+:47].[OH-:46]>>[NH2:1][C:2]1=[N:6][C:5]([c:7]2[cH:8][cH:9][c:10]([O:13][CH:14]([F:15])[F:16])[cH:11][cH:12]2)([c:17]2[cH:18][c:19]([CH2:20][N:30]3[CH2:29][CH2:28][CH2:27][CH2:31]3)[cH:22][cH:23][cH:24]2)[C:4](=[O:25])[N:3]1[CH3:26]Participants
8
Reactant 7
Product 1
Sources & evidence
- ORD record
- ord-099fad94cbfe47ca9af31a7c823bc7ae
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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