Dichloromethane → Tert-butyl 3-(1-hydroxy-2-phenylmethoxyethyl)pyrrolidine-1-carboxylate

HRID 1574536Notes

Reaction equation

HRID 1574536 reaction equation
[Ag:28]=[O:29].[Br:17][CH2:18][c:19]1[cH:20][cH:21][cH:22][cH:23][cH:24]1.[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH:10]([CH:13]([CH2:14][OH:15])[OH:16])[CH2:11][CH2:12]1.[Cl:25][CH2:26][Cl:27]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH:10]([CH:13]([CH2:14][O:15][CH2:18][c:19]2[cH:20][cH:21][cH:22][cH:23][cH:24]2)[OH:16])[CH2:11][CH2:12]1

Participants

5

Reactant 4

HCID 6344DichloromethaneHCID 7498Benzyl BromideHCID 92152Silver(II) oxideHCID 77197693Tert-butyl 3-(1,2-dihydroxyethyl)pyrrolidine-1-carboxylate

Product 1

HCID 77197930Tert-butyl 3-(1-hydroxy-2-phenylmethoxyethyl)pyrrolidine-1-carboxylate

Sources & evidence

ORD record
ord-aaaf29d3a6e146af8109171ff8aad7a9
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (1/10)

Reaction notes

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