Triethylamine → N-BOC-4-(phenylethynyl)piperidine

HRID 157522Notes

Reaction equation

HRID 157522 reaction equation
[C:1](=[O:2])([O:3][C:4]([CH3:5])([CH3:6])[CH3:7])[N:8]1[CH2:9][CH2:10][CH:11]([C:14]#[CH:15])[CH2:12][CH2:13]1.[CH3:23][CH2:24][N:25]([CH2:26][CH3:27])[CH2:28][CH3:29].[Cu:30][I:31].[I:16][c:17]1[cH:18][cH:19][cH:20][cH:21][cH:22]1>>[C:1](=[O:2])([O:3][C:4]([CH3:5])([CH3:6])[CH3:7])[N:8]1[CH2:9][CH2:10][CH:11]([C:14]#[C:15][c:17]2[cH:18][cH:19][cH:20][cH:21][cH:22]2)[CH2:12][CH2:13]1

Participants

5

Reactant 4

HCID 8471TriethylamineHCID 11575IodobenzeneHCID 24350Copper(1+) iodide; Copper(I) iodide; Cuprous iodide; Cuprous iodide (CuI)HCID 15550481tert-Butyl 4-ethynylpiperidine-1-carboxylate

Product 1

HCID 17986993N-BOC-4-(phenylethynyl)piperidine

Sources & evidence

ORD record
ord-1631603e65414288adf84640768c4a49
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

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