Bicarbonate Ion → 2,3-dihydro-2-[2-[4-(6-Fluoro-1,2-benzisoxazol-3-yl)-1-piperidinyl]ethyl]-1H-isoindol-1-one
Reaction equation
[CH2:37]([SiH:38]([CH2:39][CH3:40])[CH2:41][CH3:42])[CH3:43].[Cl:49][CH2:50][Cl:51].[F:1][c:2]1[cH:3][c:4]2[c:5]([c:6]([CH:9]3[CH2:10][CH2:11][N:12]([CH2:15][CH2:16][N:17]4[C:18](=[O:27])[c:19]5[cH:20][cH:21][cH:22][cH:23][c:24]5[CH:25]4[OH:26])[CH2:13][CH2:14]3)[n:7][o:8]2)[cH:28][cH:29]1.[Na+:48].[O-:44][C:45]([OH:46])=[O:47].[OH:30][C:31]([C:32]([F:33])([F:34])[F:35])=[O:36]>>[F:1][c:2]1[cH:3][c:4]2[c:5]([c:6]([CH:9]3[CH2:10][CH2:11][N:12]([CH2:15][CH2:16][N:17]4[C:18](=[O:27])[c:19]5[cH:20][cH:21][cH:22][cH:23][c:24]5[CH2:25]4)[CH2:13][CH2:14]3)[n:7][o:8]2)[cH:28][cH:29]1Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-7469e4b8d54c4fc4964adaeba6ca65c9
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
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