Tetrahydrofuran → N-[1-[3-(hydroxymethyl)-4-(methanesulfonamido)phenyl]ethyl]-2-methyl-2-[4-(trifluoromethyl)phenyl]cyclopropane-1-carboxamide
Reaction equation
[Al+3:37].[CH2:42]1[O:43][CH2:44][CH2:45][CH2:46]1.[CH3:1][S:2](=[O:3])(=[O:4])[NH:5][c:6]1[c:7]([C:8](=[O:9])[O:10][CH2:11][CH3:12])[cH:13][c:14]([CH:17]([CH3:18])[NH:19][C:20](=[O:21])[CH:22]2[C:23]([c:25]3[cH:26][cH:27][c:28]([C:31]([F:32])([F:33])[F:34])[cH:29][cH:30]3)([CH3:35])[CH2:24]2)[cH:15][cH:16]1.[H-:36].[H-:39].[H-:40].[H-:41].[Li+:38]>>[CH3:1][S:2](=[O:3])(=[O:4])[NH:5][c:6]1[c:7]([CH2:8][OH:9])[cH:13][c:14]([CH:17]([CH3:18])[NH:19][C:20](=[O:21])[CH:22]2[C:23]([c:25]3[cH:26][cH:27][c:28]([C:31]([F:32])([F:33])[F:34])[cH:29][cH:30]3)([CH3:35])[CH2:24]2)[cH:15][cH:16]1Participants
6
Sources & evidence
- ORD record
- ord-7ce16810e5894e4c91cf1b06e4ad1b24
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (1/10)
Reaction notes
Loading…